M Chandler, F Langbein, C Jenkins, S Schirmer. Quantum Control for Magnetic Resonance Spectroscopy. All Wales Medical Physics and Engineering Summer Meeting, poster, 2017. [PDF]
In-vivo identification of biomarkers and metabolites with MRI/S is an extremely challenging task:
- Spectral peaks frequently overlap making it difficult to differentiate certain metabolites in the spectrum.
- Various sources of noise in MRI add unclarity to the spectrum, leading to broadening and shifting of peaks, and low signal levels being lost to background noise.
Quantum control provides methods to selective excite specific proton groups in molecules. This can be exploited to avoid overlap of peaks in the spectra and clearly assign individual peaks to molecules. Moreover, pulses can be found that are robust to a range of noise sources.
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.